UBIMOTIF Fellows
15 early stage researchers from around the world have been recruited as UBIMOTIF fellows. They are enrolled as PhD students and working on research projects with one of our beneficiaries.
Maximilian Vieler
Supervisor: Ylva Ivarsson, Uppsala University
Project: Large-scale profiling of the E3 ligase specificities and the identification of functional degrons.
Home country: Germany
Background: Master in Applied Biotechnology, Uppsala University, Sweden
Aimiliani Konstantinou
Supervisor: Ylva Ivarsson, Uppsala University
Project: Explore the substrate recognition landscape of deubiquitinases.
Home country: Cyprus
Background: Master in Biomedical Sciences, University of Glasgow, Scotland
Ekaterina Isaakova
Supervisor: Petra Beli, IMB Mainz
Project: Define substrate specificity principles for ubiquitin ligases and characterize the functional role of selected ubiquitin ligase-substrate relations in proteome dynamics and quality control.
Home country: Russia
Background: Master in Applied Mathematics and Physics, Moscow Institute of Physics and Technology, Russia
Caio A B Oliveira
Supervisor: Petra Beli, IMB Mainz
Project: Investigating the function of HECT-type ubiquitin ligases in protein quality control
Home country: Brazil
Background: Master in Evolutionary Genetics and Molecular Biology, Universidade Federal de São Carlos (UFSCar), Brazil
Hazem Mamdouh
Supervisor: Norman Davey, Institute of Cancer Research
Project: Develop and apply in silico hybrid evolutionary-structural approaches and machine learning approaches to characterise the SLiM-mediated interactome.
Home country: Egypt
Background: Master in Communication and Information Technology - Informatics, Nile University, Egypt
Julia Varga
Supervisor: Ora Schueler-Furman, The Hebrew University of Jerusalem
Project: Understanding the structural basis of recognition of SLIMs in the ubiquitin system and design of inhibitory peptides.
Home country: Hungary
Background: Master in Biochemical Engineering, Budapest University of Technology and Economics, Hungary
Preethi Soundarya Sathyamurthi
Supervisor: Markus Queisser, GlaxoSmithKline
Project: Utilizing SLiMs for E3-ligases and DUBs for proximity recruitment to drug targets.
Home country: India
Background: Master in Biology – Molecular Biology and Genetics, University of Copenhagen, Denmark
Alicia Alejandra Cordova Perez
Supervisor: Yogesh Kulatho, University of Dundee
Project: Discover and characterize SLiMs that function as substrate recognition motifs in DUBs
Home country: Mexico
Background: Master in Genetic Manipulation and Molecular Cell Biology, University of Sussex, UK
Awa Diop
Supervisor: Stefano Gianni, Sapienza University of Rome
Project: Use biophysical techniques to characterize the binding kinetics of MATH and SPRY domains from E3 ligases, determine their thermodynamic stability, define their affinity with potential ligands and understand the mechanisms underlying their folding and binding.
Home country: Senegal
Background: Master in Bioinformatics, Structural Biochemistry and Genomics, Aix-Marseille University, France
Nadine Myers
Supervisor: Helena Danielson, Beactica
Project: Utilize Beactica’s SPR-based platform to develop strategies to identify hits and progressable target leads against several classes of ubiquitin ligases and DUBs.
Home country: UK
Background: Master in Biology, University of Leeds, UK
Marcel Diallo
Supervisor: Jakob Nilsson, University of Copenhagen
Project: Identification and characterization of short linear motifs that regulates ubiquitin ligases and DUBs implicated in regulating cell division.
Home country: USA
Background: Master in Science in Medical Sciences, University of Tokyo, Japan.
Sophia Park
Supervisor: Matthias Peter, ETH Zürich
Project: Identify novel ubiquitin substrates that regulate cell cycle progression using mass-spectrometry-based methods.
Home country: USA
Background: Master in Biochemistry, Scripps Research Institute in Jupiter, Florida, USA
Niels Fritsma
Supervisor: University of Tartu
Project: Investigate the roles of E3 ligases and the involvement of SLiMs during mitosis.
Home country: The Netherlands
Background: Master in Biomedical Sciences, University of Groningen, the Netherlands
Javier Arroyo Gomez
Supervisor:: Niels Mailand, University of Copenhagen
Project: Characterization of K29-linked ubiquitin chains and short linear motifs in ubiquitin signaling.
Home country: Spain
Background: Master in Molecular Techniques in Life Science, Karolinska Institutet, KTH Royal Institute and Stockholm University, Sweden.
Andrea Coti
Supervisor: Anton Khmelinskii, IMB Mainz
Project: Use experimental and computational approaches to investigate how proteins are targeted for degradation through N-terminal degradation signals.
Home country: Serbia
Background: Master in Behaviour, Evolution and Conservation, University of Lausanne, Switzerland
Marie Cadot
Supervisor: Anders Bach, University of Copenhagen
Project: Targeting Keap1 and oxidative stress in the brain using fragment-based drug discovery combined with prodrugs cleavable by reactive oxygen species and PROTACs
Home country: France
Background: PharmD, Master in Drug Design, Faculty of Pharmaceutical and Biological Sciences in Nantes, France and Faculty of Pharmaceutical Sciences in Caen, France